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Feb
2002

Signal transducer and activator of transcription 3 (STAT3) functions in cell proliferation, differentiation, and cell survival. Previously, we have demonstrated that the activation of STAT3 is required for glycoprotein 130-mediated induction of VEGF in cardiac myocytes, but the functional importance of STAT3 as an angiogenic mediator remains to be determined. To address this issue, we first generated the adenoviral vector expressing constitutively active STAT3 (caSTAT3).
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http://www.jbc.org/content/277/8/6676.full.pdf
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http://www.jbc.org/content/early/2001/12/14/jbc.M108246200.f
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http://www.jbc.org/cgi/doi/10.1074/jbc.M108246200
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Mar
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Mar
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