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Dec
1969

Variations in genes encoding several GABAreceptors have been associated with human drug and alcohol abuse. Among these, a number of human studies have suggested an association between, the gene encoding GABAreceptor β1 subunits, with Alcohol dependence (AD), both on its own and comorbid with other substance dependence and psychiatric illnesses. In the present study, we hypothesized that thegenetically-associated increased risk for developing alcoholism may be associated with impaired behavioral control and altered sensitivity to reward, as a consequence of altered brain function.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309221PMCFound
http://dx.doi.org/10.3389/fnbeh.2017.00024DOI ListingPossible


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