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Jul
2017

Imbalances in cortico-limbic activity and functional connectivity (FC) supposedly underlie biased emotional processing and present putative intermediate phenotypes (IPs) for major depressive disorder (MDD). To prove the validity of these IPs, we assessed them in familial risk. In 70 healthy first-degree relatives of MDD patients and 70 controls, brain activity and seed-based amygdala FC were assessed during an implicit emotional processing task for fMRI containing angry and fearful faces.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518910PMCFound
http://dx.doi.org/10.1038/npp.2017.59DOI ListingPossible


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