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Apr
2017

Cell-cell fusion generally requires cellular fusogenic proteins and actin-propelled membrane protrusions. However, the molecular connections between fusogens and the actin cytoskeleton remain unclear. Here, we show that the Caenorhabditis elegans fusogen EFF-1 and F-actin are enriched at the cortex of the post-embryonic fusing cells, and conditional mutations of WASP and Arp2/3 delay cell-cell fusion by impairing EFF-1 localization.
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http://www.cell.com/developmental-cell/pdf/S1534-5807(17)301
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http://www.cell.com/cms/attachment/2089721091/2075483424/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S153458071730159
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