Download: Poststreptococcal glomerulonephritis in children: clinicopathological correlations and long-term prognosis.Pediatr Nephrol 1988 Oct;2(4):381-8G Clark, R H White, E F Glasgow, C Chantler, J S Cameron, D Gill, L A Comley
Between 1962 and 1970, 36 children with acute biopsy-proven poststreptococcal glomerulonephritis (PSGN) entered a prospective long-term follow-up study. The initial biopsies were scored into four histological grades using criteria based on endocapillary proliferation, leucocyte infiltration, epithelial "hump" and crescent formation; 5 patients had grade-1 (least severe), 14 grade-2, 15 grade-3 and 2 grade-4 biopsies. Two children died from rapidly progressive glomerulonephritis; both had grade-4 biopsies.
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