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'Urticaria Solar' (331)


Jan
2018

Solar urticaria (SU) is a rare photodermatosis occurring in response to exposure to ultraviolet-A (UVA), ultraviolet-B (UVB), visible and rarely infrared light. The condition typically affects adults (median age of onset 35 years),with only one report of SU occurring in a 2-year-old.Here we present five cases of SU occurring in childhood.

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Nov
2017

Solar urticaria (SU) is a rare photodermatosis. Treatment is challenging, and outcomes are often disappointing. Omalizumab is an anti-IgE, currently approved for treatment of chronic spontaneous urticaria.

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Nov
2017

Solar urticaria is a rare type of inducible urticaria characterized by wheal and erythema formation shortly after exposure to sunlight or to an artificial light source; its pathophysiology is not yet entirely understood. The treatment of choice, in addition to exposure avoidance, consists in antihistamine administration.
This is the case of a 27-year-old woman with no personal history of allergic diseases and with a 2-year history of erythema and wheals in photo-exposed areas associated with sunlight exposure for periods longer than 10 minutes.

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Feb
2018

Omalizumab, a recombinant anti-IgE antibody, effectively treats chronic spontaneous urticaria. Evidence is lacking in patients with chronic inducible urticarias (CIndUs), which are frequently H-antihistamine resistant.
From the current published literature, we aimed to determine the strength of evidence for omalizumab efficacy and safety in the treatment of CIndUs.

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Oct
2017

Clinical trials have shown the efficacy of omalizumabs efficacy in refractory chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU), but real-life management strategies are lacking.
To assess the long-term efficacy and safety of omalizumab, and to identify predictive factors and optimum dosage regimens.
This was a prospective study of 13 patients (11 women, 2 men) with severe CSU [weekly urticaria activity score (UAS7) > 28] resistant to anti-H1 antihistamines.

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Oct
2016

[SOLAR URTICARIA].

Harefuah 2016 Oct;155(10):604-607
Fareed Sabbah, Emmilia Hodak, Assi Levi
Solar urticaria is a rare photodermatosis. It belongs to the group of physical urticarias. In this particular urticarial, erythema and whealing accompanied by pruritus occur seconds to minutes after exposure to light.

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Oct
2017

We report 3 cases of solar urticaria in which there was no response or limited response to first-line treatments with high-dose Hantihistamines or phototherapy. The patients were then treated with omalizumab. Symptoms improved in 2 patients, whose tolerance to sunlight increased considerably; quality of life clearly improved for 1 of these patients.

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Aug
2017

Afamelanotide, the first α-melanocyte-stimulating hormone (MSH) analogue, synthesized in 1980, was broadly investigated in all aspects of pigmentation because its activity and stability were higher than the natural hormone. Afamelanotide binds to the melanocortin-1 receptor (MC1R), and MC1R signaling increases melanin synthesis, induces antioxidant activities, enhances DNA repair processes and modulates inflammation. The loss-of-function variants of the MC1R present in fair-skinned Caucasians are less effectively activated by the natural hormone.

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Jun
2017

The treatment of solar urticaria is regarded as difficult. In some cases good responses to the anti-IgE antibody omalizumab (Xolair®), approved for treatment of chronic spontaneous urticaria, have been reported. We report on a 50-year-old Caucasian woman who for the last 5 years has developed localized itching and stinging erythemas following exposure to sunlight accompanied sometimes by anaphylactic reactions.

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Nov
2016

Chronic urticaria (CU) is a skin disorder defined as daily or almost daily exhibition of pruritic and transient wheals that last for 6 weeks. CU is divided into two subtypes: chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU).
To evaluate the clinical features, possible causes, associated findings, and laboratory results of different subtypes of CU in children according to a new classification.

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Mar
2017

Solar urticaria is a chronic inducible urticaria also classified as an idiopathic dermatosis. The objective of this paper is to define the phenotypic characteristics of solar urticaria and to evaluate its incidence.
This was a retrospective multicenter study in which data were gathered on the epidemiology and clinical, photobiologic, laboratory, and therapeutic characteristics of solar urticaria.

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Dec
2016

We report the case of a 53-year-old man with solar urticaria (SU) not responding to histamine antagonist therapy. Using intradermal testing with the patient's irradiated serum, we demonstrated that his SU was elicited by visible light only. This type of SU is uncommon, and makes preventive measures such as sun block largely ineffective.

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Jun
2017

Omalizumab in the Treatment of Chronic Inducible Urticaria.

Actas Dermosifiliogr 2017 Jun 5;108(5):423-431. Epub 2016 Oct 5.
P Chicharro, P Rodríguez, D de Argila
Omalizumab is a recombinant humanized monoclonal antibody that inhibits immunoglobulin E. It has been approved for the treatment of severe asthma and chronic spontaneous urticaria refractory to other treatments. Its use in the management of chronic inducible urticaria (a type triggered by certain stimuli) is still considered off-label, although this use has been discussed in some consensus papers.

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Sep
2016

Photodermatoses are typically investigated by analyzing the individual or combined effects of ultraviolet A (UVA), ultraviolet B (UVB), and visible light using light sources that simulate portions of the solar spectrum. Infrared radiation (IRR), however, accounts for 53% of incident solar radiation, but its effects are not taken into account in standard phototest protocols.
The aim was to analyze the effects of IRR, alone and combined with UVA and visible light on solar urticaria lesions, with a distinction between infrared A (IRA) and infrared B (IRB).

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Sep
2016

A case of atorvastatin-induced solar urticaria.

Photodermatol Photoimmunol Photomed 2016 Sep 5;32(5-6):317-319. Epub 2016 Oct 5.
Shoko Tajima, Atsushi Fukunaga, Chikako Nishigori

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Sep
2016

UVB (Ultra-violet B) radiation is one of the major etiological factors in various dermal pathology viz. dermatitis, actinic folliculitis, solar urticaria, psoriasis and cancer among many others. UVB causes toxic manifestation in tissues by inciting inflammatory and tumor promoting events.

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Jun
2016

Solar urticaria (SU) is an uncommon photodermatosis characterized by erythema and whealing within minutes to a few hours after exposure to sunlight or an artificial light source.
To determine the clinical features, photobiological characteristics and treatment outcomes in Thai SU patients visiting a tertiary referral hospital.
A retrospective analysis of 13 patients with SU was conducted.

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Sep
2016

Heat urticaria (HU) is a rare type of physical inducible urticaria, characterized by itchy erythema and well-demarcated weals appearing soon after heat exposure. Most cases occur in female patients aged 20-45 years. Both localized and generalized forms exist, depending on the limitation of the reaction to the skin area directly exposed to the physical stimulus or the involvement of distant sites, respectively.

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Dec
2015

Solar urticaria.

J Dtsch Dermatol Ges 2015 Dec;13(12):1250-3
Steven Goetze, Peter Elsner
Solar urticaria is a rare IgE-mediated and chromophore-dependent photodermatosis. In some cases, these chromophores, designated as "serum factor", may be detected in serum or plasma. To date, the exact pathogenesis of solar urticaria has, however, not been elucidated.

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Nov
2015

We report two cases of doxycycline-induced solar urticaria that developed shortly after initiation of therapy with persistence despite discontinuation. Consequently, dermatologists should be aware of the association between doxycycline and solar urticaria and counsel their patients on the potential for this side effect when prescribing doxycycline.

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Nov
2015

Solar urticarial (SU) is characterized by erythema, whealing, and/or pruritus occurring minutes after sun exposure. Treatment is difficult and often unsatisfactory.
To determine the action spectra and minimal urticaria dose (MUD) and to tailor a treatment regimen graded according to disease severity in a series of patients with SU.

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Nov
2015

Solar Urticaria.

J Allergy Clin Immunol Pract 2015 Sep-Oct;3(5):789-90. Epub 2015 May 13.
Hirsh D Komarow, A Robin Eisch, Michael Young, Celeste Nelson, Dean D Metcalfe

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Jul
2015

Tetracycline is a semisynthetic antibiotic and is used in several types of infections against both gram-positive and gram-negative bacteria. This therapy is often associated with phototoxic reactions that occur after exposure to UV radiation and lead to photo-onycholysis, pseudoporphyria, solar urticaria and the fixed drug eruption in the skin. The phototoxic reactions may be related to the melanin content which, on one side may bind drugs - leading to their accumulation, and on the other side, they have photoprotective and antioxidant properties.

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Apr
2015

[Diagnostic pitfalls of solar urticaria].

Ann Dermatol Venereol 2015 Apr 23;142(4):299-300. Epub 2015 Mar 23.
H Haim, H Dutartre, M Saint-Jean, A Brocard, L Peuvrel, G Quéreux, B Dréno

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Apr
2016

Three cases of solar urticaria successfully treated with omalizumab.

J Eur Acad Dermatol Venereol 2016 Apr 30;30(4):704-6. Epub 2015 Jan 30.
C Baliu-Piqué, P Aguilera Peiró

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Mar
2016

Failure of omalizumab in the treatment of solar urticaria.

J Eur Acad Dermatol Venereol 2016 Mar 29;30(3):524-5. Epub 2014 Dec 29.
S Müller, C M Schempp, T Jakob

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Nov
2014

[Angioedema and urticaria].

Ann Dermatol Venereol 2014 Nov;141 Suppl 3:S586-95
I Boccon-Gibod, L Bouillet
Angiœdema (AE) is the clinical expression of urticaria (U) which occurs when urticaria is located within the subcutis. It is a syndrome characterized by a sudden and limited subcutaneous and/or submucous swelling. The updated classification of urticaria distinguishes acute and chronic urticaria.

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Nov
2014

Physical urticaria is a subtype of chronic urticaria induced by a physical stimulus.
To evaluate the consistency between a history of physical urticaria and results of challenge testing.
Seventy-six subjects, ages 3 to 77 years old, were referred with the diagnosis of a physical urticaria and were evaluated by using challenge testing directed toward the presenting diagnosis, yet included other stimuli based on history.

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Nov
2014

Retrospective data have suggested the effectiveness of intravenous immunoglobulins (IVIG) for solar urticaria (SU).
We sought to prospectively assess the efficacy of IVIG for SU.
We conducted a multicentric phase II study to test the efficacy of a single course of IVIG (2 g/kg) in patients with severe and refractory SU.

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Dec
1969

Short sequence amino acids or oligopeptides have recently garnered attention for use as treatments for a myriad of dermatologic disorders due to their ability to effect and modulate various biological processes in the epidermis and dermis, rendering them promising candidates as medical and cosmeceutical therapeutics. Major advantages include their relative ease of synthesis and multitude of modifications that can be applied to enhance potency, affinity, specificity, hydrophilicity or hydrophobicity and cytotoxicity. Given the photoprotective effects of eumelanin on skin, there has been substantial interest in developing agents, particularly α-MSH analogs, that can induce 'sunless tanning' helping reduce risk of melanoma and non-melanoma skin cancer.

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Jul
2014

Hydroa vacciniforme and solar urticaria.

Dermatol Clin 2014 Jul 24;32(3):345-53, viii. Epub 2014 Apr 24.
Rattanavalai Nitiyarom, Chanisada Wongpraparut
Hydroa vacciniforme (HV) and solar urticaria (SU) are uncommon immunologically mediated photodermatoses. HV occurs almost exclusively in children, usually beginning in childhood and remitting spontaneously by adolescence. Association with chronic Epstein-Barr virus infection has been reported in HV, which raises the possibility of lymphoproliferative disorders in these patients.

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Jul
2014

Evaluation of patients with photodermatoses.

Dermatol Clin 2014 Jul 5;32(3):267-75, vii. Epub 2014 May 5.
David Choi, Swati Kannan, Henry W Lim
The systematic evaluation of photosensitive patients involves a comprehensive history, physical examination, phototesting, and, if necessary, photopatch testing and laboratory evaluation. Polymorphous light eruption, chronic actinic dermatitis, solar urticaria, and photosensitivity secondary to systemic medications are the most commonly encountered photodermatoses in dermatology clinics worldwide.

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Dec
1969

Melanoma incidence continues to rise due to intentional exposure to ultraviolet radiation (UVR) from sunlight and indoor tanning beds. Eumelanin exhibits photoprotective effects; thus, agents that induce its synthesis offer a means for sunless tanning without UVR damage. Herein, we report the development of two pentapeptides, P9 and P10, capable of enhancing melanin synthesis in B16 melanoma cells by activating mushroom and mouse tyrosinases without any effect on cell viability or proliferation.

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Apr
2014

Solar urticaria is a type of inducible urticaria triggered by sun exposure resulting in hives on exposed skin as well as risk of developing systemic symptoms. Most cases are reported in the adult population. However, cases do occur in children.

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