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Feb
2018

The Receptor Interacting Protein Kinases in the Liver.

Semin Liver Dis 2018 Feb 22;38(1):73-86. Epub 2018 Feb 22.
Lily Dara
The receptor interacting serine/threonine kinase1 and 3 (RIPK1, RIPK3) are regulators of cell death and survival. RIPK1 kinase activity is required for necroptosis and apoptosis, while its scaffolding function is necessary for survival. Although both proteins can mediate apoptosis, RIPK1 and RIPK3 are most well-known for their role in the execution of necroptosis via the mixed lineage domain like pseudokinase.

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Dec
1969

Author Index Vol. 12, No. 1-3, 2018.

Sex Dev 2018 22;12(1-3):158. Epub 2018 Feb 22.

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Feb
2018

Due to an unfortunate turn of events, the initials of the third author appeared incorrectly in the original publication as the name should have read T Kondo.

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Feb
2018

The original version of abstract PO-162 "Chronic Granulomatous Disease in a Brazilian Patient Mimetizing Sarcoidosis" incorrectly listed the name of the second author as Micheli Barsioti. The correct spelling of the author's name is Michele Baziotti Man.

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Feb
2018

In the original publication of the article, the author's name "Prof. René Daher" was inadvertently missed in the author group. This has been updated in this erratum.

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Feb
2018

There has been a steady increase in cultural competency training in medical education programmes worldwide. To provide high-quality culturally competent care and reduce health disparities between Māori and non-Māori in New Zealand, several health models have been devised. The Indigenous Health Framework (IHF), currently taught at the University of Otago, Christchurch undergraduate medical programme, is a tool developed to assist health professionals to broaden their range of clinical assessment and communicate effectively with Māori patients and whānau, thereby improving health outcomes and reducing disparities.

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Feb
2018

Perindopril arginine and Indapamide hemihydrate in combination were proven to have a synergistic antihypertensive impact when compared with the use of each component alone. Therefore, a new Ultra-High Performance Liquid Chromatography coupled with Ultraviolet detector (UHPLC-UV) method has been developed and subsequently validated for simultaneous determination of the anti-hypertensive combination of Perindopril arginine and Indapamide hemihydrate. The separation of Perindopril arginine and Indapamide hemihydrate was achieved using a BEH C18 (1.

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Feb
2018

The function of the neuromuscular junction in children is amenable to electrophysiological testing. Of the two tests available, repetitive nerve stimulation is uncomfortable and has a reduced sensitivity compared with single-fibre methodology. The latter is the method of choice, recording the variability in neuromuscular transmission as a value called jitter.

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Feb
2018

Diets contain secondary plant metabolites commonly referred to as phytochemicals. Many of them are believed to impact human health through various mechanisms, including protection against oxidative stress and inflammation, and decreased risks of developing chronic diseases. For mothers and other people, phytochemical intake occurs through the consumption of foods such as fruits, vegetables, and grains.

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Feb
2018

Tetrodotoxin (TTX), the mode of action of which has been known since the 1960s, is widely used in pharmacology as a specific inhibitor of voltage-gated sodium channels (Nav channels). This toxin has contributed to the characterization of the allosteric model of the Nav channel, and to discriminating TTX-sensitive and TTX-resistant subtypes. In addition to its role as a pharmacological tool, TTX is now considered a therapeutic molecule, and its development should lead to its use in certain pathologies involving Nav channels, particularly in the field of pain.

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Feb
2018

The body mass index (BMI) is unsatisfactory in being affected by both relative leg length and height, and, for use with children and adolescents, therefore needs to be interpreted in relation to age. The sitting-height index of build (body mass)/(sitting height)³, is largely free of these disadvantages. Furthermore, because that index is independent of relative leg length, the latter can be treated as a separate indicator of nutritional history and health risks.

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Feb
2018

This article describes our experience participating in a multisite collaborative study involving frontline nurses and operational failures (OFs). We encountered a range of challenges conducting the study as proposed by the study's coordinating center (CC), which hindered our ability to meet our goals and objectives. We identified 3 general areas in which our expectations and actual experience diverged: 1) research resources, design, and methods; 2) CC communications and deliverables; and 3) influencing organizational change.

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Feb
2018

The purpose of this project was to identify key behaviors and attributes that distinguish high-performing nurses to develop a tool for employment screening, staff development, and performance management.
Selecting nurses who will complement an organization's mission and philosophy is a key step toward achieving quality and safety goals, ensuring patient and family satisfaction, and improving retention rates and overall costs.
Focus group methodology was used to determine perceptions of high-performing nurses' behaviors and attributes.

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Feb
2018

The aims of this study were to illustrate the quality, safety, cost-effectiveness, and ethics of consumer engagement initiatives and identify promising practices and leadership strategies used by nursing leaders.
A literature review was performed with supplementary interviews conducted with 25 key nursing informants including nursing executives and chief nursing officers at acute care hospitals, community health centers, policy institutions, and quality and safety organizations. A narrative synthesis approach was used to identify and compare existing measures of consumer engagement and compassionate care in acute care settings.

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Feb
2018


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Mar
2018

Family matters.

JAAPA 2018 Mar;31(3):58
Cameron Young Sweeney

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Mar
2018

Acute epididymitis.

JAAPA 2018 Mar;31(3):50-51
Shaun Lynch

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Mar
2018

At a VA hospital, wait times for gastroenterology care have been in the order of 60 to 90 days for new clinic consults. Through a quality improvement process, these times were reduced to less than 30 days. With a revised triage process, the number of consults needing to be scheduled into the clinic was reduced 34%.

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Mar
2018

Anorectal pain and discomfort are common complaints in the general population, and can stem from a number of possible causes. Often, the complaints present in the primary care setting and can be adequately evaluated, diagnosed, and treated without the need for referral to a colorectal specialist. Proper evaluation and diagnosis can result in prompt, effective patient care.

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Mar
2018

Although early initiation of human milk (HM) expression after birth is known to increase lactation success in mothers of very low birthweight (VLBW) infants, initiation is frequently delayed, potentially decreasing both short- and long-term HM production. Obstetrical (OB) nurses are typically the healthcare provider responsible for facilitating the initial HM expression session. As delays in initiation are common, it is likely that nurses experience obstacles to facilitation of an early initiation of HM expression.

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Mar
2018

Pregnancy after Solid Organ Transplantation.

MCN Am J Matern Child Nurs 2018 Mar/Apr;43(2):89-96
Jane M Kurz
To explore the reproductive decision-making process with women who were organ transplant recipients (renal, lung, & heart transplants).
Grounded theory guided data collection and analyses. Mixed methods with audiotaped telephone interviews and a written survey measuring social support were used.

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Mar
2018

Posterior reversible encephalopathy syndrome (PRES) is a newly defined syndrome; therefore, this transient clinical condition is not well known and probably underdiagnosed. It develops quickly with symptoms that are usually indistinguishable from eclampsia. Nurses need to be knowledgeable and aware of identifying symptoms and appropriate treatment.

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Mar
2018

Death with Dignity (and Love).

Am J Nurs 2018 Mar;118(3):72
Laurie Barkin
A nurse takes on a challenging new role at her ailing father's request.

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Mar
2018

: This article is part of a series, Supporting Family Caregivers: No Longer Home Alone, published in collaboration with the AARP Public Policy Institute. Results of focus groups, conducted as part of the AARP Public Policy Institute's No Longer Home Alone video project, supported evidence that family caregivers aren't given the information they need to manage the complex care regimens of family members. This series of articles and accompanying videos aims to help nurses provide caregivers with the tools they need to manage their family member's health care at home.

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Mar
2018

: The competing demands of caring for high-acuity patients, reducing health care costs, and improving access to specialty care are complex challenges facing all health care providers. One approach-empowering nurses to expand their scope of practice-has been successfully employed for two decades by the nurse and physician leadership of a neurology department in an urban academic medical center. This article discusses the department's implementation of a quality improvement initiative to enhance access to neurology services in an ambulatory clinic by extending nursing practice to include lumbar puncture.

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Mar
2018

Editor's note: On July 26, 2017, Alex Wubbels, the charge nurse on the burn unit at the University of Utah Hospital in Salt Lake City, was arrested for refusing to allow a police officer to draw blood from an unconscious patient in her care. Her arrest, during which she was forcefully placed in handcuffs and dragged out of the hospital, was documented on body camera video and drew national attention. We asked our ethical and legal contributing editors to provide some insight on the issues of this case.

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Mar
2018

Conversation.

Am J Nurs 2018 Mar;118(3):33
Simona Carini

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Mar
2018

Strategies to address this potent barrier to treatment and prevention.

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Mar
2018

World Kidney Day and International Women's Day 2018 are commemorated on the same day (March 8), an opportunity to highlight the importance of women's health, and particularly, their kidney health. On its 13th anniversary, World Kidney Day promotes affordable and equitable access to health education, health care, and prevention for all women and girls in the world. In this article, we focus on what we do and do not know about women, kidney health, and kidney disease, and what we might learn in the future to improve outcomes worldwide.

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Mar
2018

AIntradialytic hypotension (IDH) occurring during hemodialysis (HD) may cause severe complications and can be life-threatening. IDH is a common symptom in patients with end stage renal disease undergoing HD. Currently, no effective predictive models for IDH exist.

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Mar
2018

Individuals with kidney failure on outpatient hemodialysis therapy may experience many biopsycho social complications and existential concerns. Consequently, there is a need to implement a process of advance care planning to effectively meet the extensive needs of these individuals. However, this article suggests there are various barriers in some outpatient hemodialysis facilities that may hinder the introduction of advance care planning.

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Mar
2018

Pain is a major problem for individuals undergoing hemodialysis and can lead to decreased quality of life when ineffectively managed. Pain is often reported as burdensome; thus, nurses must learn effective, nonpharmacological adjuncts to help care for symptomatic patients. The purpose of this review was to identify non-pharmacologic complementary therapies and evaluate their effectiveness in minimizing pain among individuals undergoing hemodialysis.

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Feb
2018

Gabrielle Lévy and the Roussy-Lévy syndrome.

J Hist Neurosci 2018 Feb 22:1-28. Epub 2018 Feb 22.
Peter J Koehler
In 1934, Gabrielle Lévy died at the age of 48. She became well known for an article she published on a hereditary polyneuropathy in cooperation with Gustav Roussy, resulting in the eponym Roussy-Lévy syndrome. Not much is known about this extraordinary neurologist/neuropathologist.

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Apr
2017

To investigate the Demodex infection status and influencing factors in medical students in Wuhu City.
The mite specimens were collected by the cellophane tape method, and the influencing factors were investigated through the questionnaires.
A total of 316 medical students were surveyed, 117 students were infected with Demodex mite, and the total infection rate was 37.

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May
2017

To explore the anti-tumor effect of 17XL strains of(P.y) infection on melanoma in mice.
B16F10 tumor cells were axillarilly injected into the right flank of 20 C57BL/6 mice to establish tumor-bearing mouse models.

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Mar
2017

To understand the spatial distribution characteristics of wild feces in schistosomiasis endemic areas of Jiangling County, Hubei Province and further explore the source of infection efficiently, so as to provide the evidence for the development of corresponding monitoring and response technology.
In 2011, the fresh wild feces were investigated every two months in the selected 15 villages by the severity of historical endemic in Jiangling County. The schistosome miracidium hatching method was used to test the schistosome infection of the wild feces.

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Dec
2017

To study the prokaryotic expression and immune protection of triosephosphate isomerase (TPI) ofin mice.
Total RNA was extracted from toxoplasma tachyzoites, and TPI fragment was amplified by PCR and cloned into the prokaryotic expression vector pET-28a (+). The target protein was induced with IPTG and purified by Ni-NTA affinity chromatography.

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Aug
2017

To explore the strategy and countermeasures ofsnail control and evaluate the effect in inside-embankment areas of lake-type schistosomiasis endemic area, for providing the effective method for controlling and interrupting the schistosomiasis transmission.
The data of schistosomiasis epidemic and its control and prevention were collected in Junshan District, Hunan Province, and the effect of snail control countermeasures were evaluated and the trend of indexes of snails was drafted in the inside-embankment areas of Junshan District, Hunan Province from 1998 to 2007.
The area with snails in the inside embankment areas of Junshan District decreased by 98.

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Apr
2017

To investigate the malaria knowledge of CDC staff and their demands on related training in malaria non-endemic areas, so as to provide the reference for planning the appropriate curriculum.
All the participants who were the staff of county CDCs all over Qinghai Province and attended the provincial training workshop were surveyed. A self-administered questionnaire survey was carried out and the data was statistically analyzed.

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Mar
2017

To analyze the clinical features of 6 patients with imported schistosomiasis mansoni, including the epidemic history, clinical manifestations, laboratory tests and therapeutic effect, so as to provide references for improving the levels of diagnosis and treatment of physicians.
The clinical data of 6 patients with imported schistosomiasis mansoni from January 2009 to July 2016 were collected and analyzed.
All the 6 imported patients with schistosomiasis mansoni had a clear history of cercarial infested water exposure.

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Feb
2018

In the original publication, Page 3, Sect. 4.3, the first sentence was incorrectly published.

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Feb
2018

A puzzling interaction involving alertness and cognitive control is indicated by the finding of faster performance but larger congruency effects on alert trials (on which alerting cues are presented before the task stimuli) than on no-alert trials in selective attention tasks. In the present study, the author conducted four experiments to test hypotheses about the interaction. Manipulation of stimulus spacing revealed a difference in congruency effects between alert and no-alert trials for narrowly spaced stimuli but not for widely spaced stimuli, inconsistent with the hypothesis that increased alertness is associated with more diffuse attention.

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Feb
2018

The author would like to correct the errors in the publication of the original article. The corrected details are given below for your reading.

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Feb
2018

In response to changes in health care, American medical schools are transforming their curricula to cultivate empathy, promote professionalism, and increase cultural competency. Many scholars argue that an infusion of the humanities in premedical and medical training may help achieve these ends. This study analyzes Web-based messaging of Ohio's undergraduate institutions to assess premedical advising attitudes toward humanities-based coursework and majors.

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Feb
2018

Very few studies have examined quality of life (QOL) in elderly carers of orphaned children in African settings. This study explored sociodemographic factors and health-related characteristics that influence QOL of grandparent carers in Zimbabwe. A cross-sectional study stratified by district was done to collect information on socioeconomic factors, health-related characteristics, and QOL of grandparent carers (= 327; age:= 62.

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Feb
2018

Repetitive Questioning II.

Gerontol Geriatr Med 2018 Jan-Dec;4:2333721417740190. Epub 2018 Feb 13.
R C Hamdy, A Kinser, A Depelteau, J V Lewis, R Copeland, T Kendall-Wilson, K Whalen
Repetitive questioning is a major problem for caregivers, particularly taxing if they are unable to recognize and understand the reasons why their loved one keeps asking the same question over and over again. Caregivers may be tempted to believe that the patient does not even try to remember the answer given or is just getting obnoxious. This is incorrect.

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Feb
2018

Human granulocytic anaplasmosis (HGA) is a tick-borne, infectious disease caused bythat generally presents with nonspecific symptoms such as fever, chills, headache, malaise, and myalgia. If not treated immediately, HGA can cause hemophagocytic lymphohistiocytosis (HLH), a well-documented but underrecognized sequela of severe HGA. In this article, we report a case of severe HGA with hyperferritinemia in a 74-year-old male from Central Pennsylvania who initially presented with recurrent fevers, nausea, and malaise to our emergency department and was subsequently discharged home that same day.

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Feb
2018

Severe Pulmonary Hypertension Due to Adult-Onset Still's Disease.

J Investig Med High Impact Case Rep 2018 Jan-Dec;6:2324709618757260. Epub 2018 Feb 13.
Ankur Sinha, Ravikaran Patti, Paurush Ambesh, Chukwudi Obiagwu, Namrita Malhan, Kabu Chawla
A 29-year-old female with adult-onset Still's disease (AOSD) presented with progressive shortness of breath both on rest and on exertion, increased abdominal girth, and swelling in both legs. She was on oral prednisone and was recently started on canakinumab (interleukin-1 antagonist) for joint pain and rash of AOSD. Echocardiogram showed severely dilated right ventricle, dilated pulmonary artery, moderately reduced right ventricular systolic function, but with normal left ventricular systolic function.

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