Author: Dionizio M Ramos-Filho (1)
Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice.Br J Nutr 2017 Jul 11;118(1):41-52. Epub 2017 Aug 11.Patricia C de Velasco, Gustavo Chicaybam, Dionizio M Ramos-Filho, Raísa M A R Dos Santos, Caroline Mairink, Fátima L C Sardinha, Tatiana El-Bacha, Antonio Galina, Maria das Graças Tavares-do-Carmo
The quality of dietary lipids in the maternal diet can programme the offspring to diseases in later life. We investigated whether the maternal intake of palm oil or interesterified fat, substitutes for trans-unsaturated fatty acids (FA), induces metabolic changes in the adult offspring. During pregnancy and lactation, C57BL/6 female mice received normolipidic diets containing partially hydrogenated vegetable fat rich in trans-unsaturated fatty acids (TG), palm oil (PG), interesterified fat (IG) or soyabean oil (CG).
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