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Author: Flavio F Demarco (42)


Feb
2018

Assess the influence of anxiety symptoms on oral health related-quality of life in young women from a cohort study in Southern Brazil.
A sample of 535 young mothers were analyzed. Interviews and psychological evaluations were carried out by trained psychologists.

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Feb
2018

Although the biological properties of mesenchymal stem cells (MSC) are well-characterized in vitro, MSC clinical application is still far away to be achieved, mainly due to the need of xenogeneic substances for cell expansion, such as fetal bovine serum (FBS). FBS presents risks regarding pathogens transmissions and internalization of animal's proteins, which can unleash antigenic responses in patients after MSC implantation. A wide range of venous blood derivatives (VBD) has been reported as FBS substitutes showing promising results.

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Nov
2017

To test whether maternal education has a direct effect on gingival bleeding in adolescents aged 12 and to assess whether oral health behaviours over time mediate that association.
Two oral health studies nested in the 1993 Pelotas (Brazil) birth cohort study were carried out in participants aged 6 (n = 359) and 12 years (n = 339). The proportion of teeth with bleeding on probing (BOP) and the median number of teeth with gingivitis at age 12 were recorded.

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Jan
2018

This study aimed to evaluate the quality of posterior restorations (amalgam or composite) placed in adults from a birth cohort and its association with clinical and socioeconomic determinants experienced during their life course.
A representative sample (n=539) of all 5914 births occurring in Pelotas (Brazil) in 1982 was prospectively investigated. Quality of posterior restorations (satisfactory or unsatisfactory) was assessed at 31 yrs-old, using modified USPHS criteria.

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Oct
2017

To systematically review the literature in order to investigate a potential association between periodontitis and halitosis.
Electronic searches were performed in four different databases: PubMed, Scopus, Web of Science and Scielo. Population-based observational studies that tested the association between periodontitis and halitosis were included.

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Jan
2018

This study aims to conduct a systematic review to determine the prevalence of halitosis in adolescents and adults.
Electronic searches were performed using four different databases without restrictions: PubMed, Scopus, Web of Science, and SciELO. Population-based observational studies that provided data about the prevalence of halitosis in adolescents and adults were included.

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Aug
2017

Prediction of periodontitis development is challenging. Use of oral health-related data alone, especially in a young population, might underestimate disease risk. This study investigates accuracy of oral, systemic, and socioeconomic data on estimating periodontitis development in a population-based prospective cohort.

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May
2017

This systematic review and meta-analysis evaluated the association between developmental defects of enamel and dental caries in the primary dentition.
Electronic searches were performed in PubMed, Web of Knowledge, Scopus and Scielo for the identification of relevant studies.
Observational studies that examined the association between developmental defects of enamel and dental caries in the deciduous dentition were included.

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Mar
2017

We aimed to estimate hypothetical effects of habits (smoking, alcohol consumption, and fat and carbohydrates consumption) combined with diet-induced overweight/obesity on the risk of periodontitis. The risk of any periodontitis, moderate/severe periodontitis, and the combination of bleeding on probing (BOP) and clinical attachment loss (CAL) was estimated using the parametric g-formula in adults aged 31 years from the 1982 Pelotas Birth Cohort in Brazil. Individuals in this cohort have been followed since birth.

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Apr
2016

This study evaluated the influence of 2-hydroxyethyl methacrylate (HEMA) on the degree of conversion (DC) and cytotoxicity of a dental bonding resin (DBR).
A monomer mixture based on 61.9 wt% of bisphenol A glycidyl methacrylate (Bis-GMA), 36.

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May
2016

The aim of this study was to systematically review the literature to answer the questions: (i) "Is periodontal treatment effective to improve clinical and immunological conditions in obese subjects?"; (ii) "Do obese subjects present different clinical and immunological response after periodontal therapy when compared to non-obese subjects?"
Searches were performed in six databases up to August 2014. Interventional studies were included if the following data were described: (1) Obesity/overweight assessment; (2) definition of periodontal disease; (3) periodontal therapy; (4) inflammatory marker in serum/plasma, and/or clinical parameters of periodontal disease. Assessment of quality was performed with the Downs and Black scale.

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Dec
2015

This study aimed to assess the impact of use of and need for dental prosthesis (DP) on oral health related quality of life (OHRQoL) among Brazilian adults and elders.
This cross-sectional, population-based study, used data from the Brazilian Oral Health National Survey performed in 2010. The sample was representative of adults (35-44 years of age) and elders (65-74 years) at national level.

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Dec
1969

Although children spend most of their time involved in activities related to school, few studies have focused on the association between school social environment and oral health. This cross-sectional study assessed individual and school-related social environment correlates of dental caries in Brazilian schoolchildren aged 8-12 years.
A sample of children from 20 private and public schools (n=1,211) was selected.

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Oct
2015

In this study the literature was systematically reviewed to investigate the clinical longevity of anterior composite restorations.
Clinical studies investigating the survival of anterior light-cured composite restorations with at least three years of follow-up were screened and main reasons associated with restoration failure were registered.
PubMed, Scopus, and Cochrane databases were searched without restriction on date or language.

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Sep
2015

To systematically review the literature in order to identify an association between income and tooth loss in adults.
An electronic search was conducted on PubMed, Scopus, Embase, Web of Knowledge, Scielo and LILACS. Studies were included if they reported the relationship between socioeconomic status (assessed by income) and tooth loss (clinical examination or self-reported) among adults aged from 18 to 60-years-old.

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Jun
2015

This study aimed to conduct a systematic review assessing the effects of weight gain on the incidence of periodontitis in adults.
Electronic searches in four databases were performed up to and including February 2015. Only prospective longitudinal studies assessing the association between weight gain and the incidence of periodontitis in adults were eligible to be included in this study.

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Jun
2015

Advantages and disadvantages of using intermediate layers underneath resin-composite restorations have been presented under different perspectives. Yet, few long-term clinical studies evaluated the effect of glass-ionomer bases on restoration survival. The present study investigated the influence of glass-ionomer-cement base in survival of posterior composite restorations, compared to restorations without base.

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May
2015

This systematic review and meta-regression analysis aimed to calculate a combined prevalence estimate and evaluate the prevalence of different Treponema species in primary and secondary endodontic infections, including symptomatic and asymptomatic cases.
The MEDLINE/PubMed, Embase, Scielo, Web of Knowledge, and Scopus databases were searched without starting date restriction up to and including March 2014. Only reports in English were included.

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Dec
1969

Periodontal disease is ranked among the 10 most prevalent chronic diseases worldwide, and is considered a major public health problem. Its etiology has been associated with local and general conditions that could interfere in the host immune response. Obesity, like periodontal disease, has emerged as a prevalent chronic disease in high-, low- and medium-income countries, recognized as risk factor for cardiovascular disease and cancer.

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Dec
1969

This study aimed to evaluate the factors associated with the decision to attend an academic post-graduation program by dental students. A cross-sectional study was conducted in 2012, last-year undergraduate students from Dental Schools of Southern Brazil. A closed questionnaire was applied including questions grouped in three different blocks: pre-graduate, undergraduate period and future perspectives.

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Dec
2013

This cross-sectional study aimed to assess the relationship between weight status and gingival inflammation in Brazilian schoolchildren aged 8- to 12-year old, when controlling for potential confounders.
Overall, 1211 children aged 8- to 12-year old from public and private schools in Southern Brazil were selected by a two-stage cluster method. Questionnaires were used to assess socio-demographic data and oral hygiene habits.

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Nov
2013

This retrospective, longitudinal clinical study investigated the longevity up to 20 years of posterior restorations placed with 3 universal composites (Charisma, Herculite XR, Z100) and of anterior restorations placed with 2 universal composites (Charisma, Herculite XR).
Records from 90 patients were retrieved from a private practice (374 posterior, 219 anterior restorations). Clinical evaluation was performed by the FDI criteria.

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Mar
2015

The aim of the present study was to describe oral health-related quality of life (OHRQoL) and associated factors in elderly individuals treated at Family Health Units in urban areas of the city of Pelotas, Brazil.
The sample was composed of 438 individuals aged 60 years old or older. Demographic, socio-economic, general health and behavioural variables were collected using standardised questionnaires.

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Dec
2012

Telomeres are protective structures located at the end of eukaryotic chromosomes which are shortened after each cell division, leading to senescence. Telomerase activity prevents telomere shortening by reverse transcription catalyzed by the subunit called TERT (telomerase reverse transcriptase). TERT expression has shown interesting cellular properties, which may be appealing for tissue engineering, such as the enhancement of cell proliferation and differentiation abilities in vitro.

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Oct
2012

The purpose of the study was to investigate the influence of a child's clinical condition; maternal characteristics such as dental anxiety and dental visit pattern; socioeconomic conditions; and maternal perception of the child's oral health-related quality of life (OHRQoL) on a child's use of dental care services.
A cross-sectional study of 608 mother-child dyads was conducted during the Children's Immunization Campaign in Pelotas, Brazil. Mothers answered a questionnaire regarding their use of dental services, dental anxiety (Dental Anxiety Scale), socioeconomic status, and perception of their children's OHRQoL (the Early Childhood Oral Health Impact Scale).

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Jan
2012

Resin composites have become the first choice for direct posterior restorations and are increasingly popular among clinicians and patients. Meanwhile, a number of clinical reports in the literature have discussed the durability of these restorations over long periods. In this review, we have searched the dental literature looking for clinical trials investigating posterior composite restorations over periods of at least 5 years of follow-up published between 1996 and 2011.

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Jan
2012

The aim of this study was to assess the occurrence of incidents involving the craniofacial region during Brazilian Professional Soccer League matches. The mechanisms of these incidents and the association between their characteristics and severity were also analyzed.
Prospective Epidemiology Study.

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Mar
2012

Most studies comparing prevalence of periodontal disease and risk factors by using partial protocols were performed in adult populations, with several studies being conducted in clinical settings. The aim of this study is to assess the accuracy of partial protocols in estimating the prevalence of periodontal outcomes in adolescents and young adults from two population-based birth cohorts from Pelotas, Brazil, and to assess differences in the estimation and strength of the effect measures when partial protocols are adopted compared to full-mouth examination.
Gingival bleeding at probing among adolescents (n = 339) and young adults (n = 720) and dental calculus and periodontal probing depth among young adults were assessed using full-mouth examinations and four partial protocols: Ramfjord teeth (RT), community periodontal index (CPI), and two random diagonal quadrants (1 and 3, 2 and 4).

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Oct
2011

This retrospective longitudinal study investigated the longevity of posterior restorations placed in a single general practice using 2 different composites in filler characteristics and material properties: P-50 APC (3M ESPE) with 70vol.% inorganic filler loading (midfilled) and Herculite XR (Kerr) with 55vol.% filler loading (minifilled).

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Jun
2012

This in vivo study evaluated the influence of controlled diabetes on biofilm formation on a soft denture liner in elderly patients.
Soft denture lining materials are more susceptible to microbial colonisation than denture base acrylic resins. Especially in the elderly, several predisposing factors may accumulate leading to an increased probability of biofilm development that may result in candidiasis, a significant clinical oral disease.

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Nov
2010

Dental pulp tissue engineering is an emerging field that can potentially have a major impact on oral health. However, the source of morphogens required for stem cell differentiation into odontoblasts and the scaffold characteristics that are more conducive to odontoblastic differentiation are still unclear. This study investigated the effect of dentin and scaffold porogen on the differentiation of human dental pulp stem cells (DPSCs) into odontoblasts.

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Jul
2009

This study investigated the impact of immediate and delayed light activation on self-polymerization of a model dual-cured luting agent. The material presented the following components: base paste - 2,2-bis[4-(2-hydroxy-3-methacryloxyprop-1-oxy)phenyl]propane/triethylene glycol dimethacrylate (TEGDMA), camphorquinone, dimethyl-p-toluidine, butylated hydroxytoluene (BHT), glass fillers; catalyst paste - bisphenol-A ethoxylated dimethacrylate/TEGDMA, benzoyl peroxide, BHT, fillers. The pastes were mixed and seven polymerization scenarios tested: immediate light activation using low (5Jcm(-2)) or high (20Jcm(-2)) energy dose; delayed light activation (after 2min - short delay) using low or high dose; delayed light activation (after 10min - long delay) using low or high dose; and self-polymerization only.

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May
2008

Fluoride has been recognized as a desensitizer; however, no study has addressed its effects to decrease tooth sensitivity when compared with a placebo in a double-blind randomized clinical study.
The authors divided 30 participants into two groups: one that received a placebo and another that was treated with fluoride. All patients used 16 percent carbamide peroxide (CP) in a custom-fitted tray until their teeth achieved shade A1 or lighter.

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Jul
2008

This study evaluated the effect of organic solvent concentration on the polymerization kinetics for a model dental adhesive resin containing a ternary photoinitiator system. A monomer blend based on the bis-GMA, TEGDMA, and HEMA was used as a model dental adhesive resin, which was polymerized using a binary system [camphorquinone (CQ) and ethyl 4-dimethylamine benzoate (EDAB)] and a ternary system [CQ, EDAB, and diphenyliodonium hexafluorphosphate (DPIHFP)]. Additionally, these blends had 0, 10, 20, 30, and 40 wt % ethanol added.

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Sep
2007

Cavity preparations have routinely been associated with decreased fracture strength of restored teeth.
The purpose of this study was to evaluate the influence of endodontic treatment and thermal cycling on the fracture resistance of teeth restored with ceramic or composite resin inlay restorations.
One hundred sound, maxillary premolars were selected.

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Feb
2007

To evaluate the pulp response to direct capping with self-etching adhesive systems using sodium hypochlorite as a hemostatic agent.
Twenty-six human third molars scheduled for extraction were selected from undergraduate students of dentistry. Class I cavities with pulp exposures were performed.

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Feb
2007

This study investigated the influence of internal surface treatment and margin location on the microleakage of 2 alumina-reinforced ceramic crown systems: In-Ceram (VITA Zahnfabrik) and Procera (Nobel Biocare). Full crowns were produced for each of the 2 systems (n = 24) in human premolars, with margins located in enamel and dentin, and luted with Single Bond and RelyX ARC (3M ESPE). Four internal ceramic treatments were tested: (1) aluminum oxide blasting (AO), (2) AO plus silane, (3) hydrofluoric acid etching (HF), and (4) HF plus silane.

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Jun
2007

Characterize the microstructure, composition and some physical properties of a glass-infiltrated alumina/zirconia-reinforced ceramic (IZ) and the effect of surface treatment on topography.
IZ ceramic specimens were fabricated according to ISO6872 instructions and polished through 1 microm alumina abrasive. Quantitative and qualitative analyses were performed using scanning electron microscopy (SEM), backscattered imaging (BSI), electron dispersive spectroscopy (EDS) and stereology.

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Oct
2006

The aim of this study was to investigate the expression of 2 extracellullar matrix glycoproteins, fibronectin (FNC) and tenascin (TNC), following direct pulp capping with calcium hydroxide (CH). Third molars scheduled for extraction were used. Standardized class I cavities with pulp exposures were prepared.

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Oct
2006

This in vitro study evaluated the fracture resistance of teeth restored with different designs of partial ceramic restorations using two diameters of steel ball to apply fracture stresses. One hundred and twenty sound maxillary premolars were randomly divided into three groups of 40 elements; each group was submitted to one of three indirect restoration designs: inlay, onlay with only lingual cuspal coverage and onlay with buccal and palatal cuspal coverage. Another 20 intact teeth were randomly assigned as control groups.

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Dec
2002

The aim of this study was to evaluate the influence of caries-detecting dyes on the microleakage of adhesive materials. Sixty cubic class V cavities were prepared on buccal and lingual surfaces of 30 human third molars. Coronal margins were located in enamel and gingival margins in cementum.

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