Author: Lother Lucka (1)
Interleukin-1β induces an inflammatory response and the breakdown of the endothelial cell layer in an improved human THBMEC-based in vitro blood-brain barrier model.J Neurosci Methods 2014 May 14;228:35-45. Epub 2014 Mar 14.Josephine Labus, Sonja Häckel, Lother Lucka, Kerstin Danker
The blood-brain barrier is necessary to provide an optimal environment for cerebral function. It consists of endothelial cells that interact through interendothelial tight junctions and form a barrier with low permeability. Therefore, the infiltration of lymphocytes into the central nervous system is limited.
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