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Author: M Aubert (471)



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Mar
2009

Modeling tumor cell migration: From microscopic to macroscopic models.

Phys Rev E Stat Nonlin Soft Matter Phys 2009 Mar 25;79(3 Pt 1):031917. Epub 2009 Mar 25.
Christophe Deroulers, Marine Aubert, Mathilde Badoual, Basil Grammaticos
It has been shown experimentally that contact interactions may influence the migration of cancer cells. Previous works have modelized this thanks to stochastic, discrete models (cellular automata) at the cell level. However, for the study of the growth of real-size tumors with several million cells, it is best to use a macroscopic model having the form of a partial differential equation (PDE) for the density of cells.

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Jun
2009

The virological synapse (VS) is a specialized molecular structure that facilitates the transfer of certain lymphotropic viruses into uninfected T cells. However, the role of the VS in the transfer of nonlymphotropic viruses into T cells is unknown. Herpes simplex virus (HSV) has been shown in vitro to infect T cells and modulate T-cell receptor function, thereby suppressing T-cell antiviral function.

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