Helping You Find Full Text Journal Articles

Search Results:

Author: Ntobeko A B Ntusi (14)


Jan
2018

Rheumatoid arthritis (RA) is a multi-system, autoimmune disorder and confers one of the strongest risks for cardiovascular disease (CVD) morbidity and mortality.
To assess myocardial function and vascular stiffness in RA patients with and without cardiovascular risk factors (CVRFs) using cardiovascular magnetic resonance (CMR).
23 RA patients with no CVRFs (17 female, mean age 52±13 years), 46 RA patients with CVRFs (32 female, mean age 53± 12), 50 normal controls (32 female, mean age 50±11 years), and 13 controls with CVRFs (7 female, mean age 55±7 years), underwent CMR at 1.

View Full Text PDF Listings View primary source full text article PDFs.

Sep
2016

The survival of patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) who have access to highly active antiretroviral therapy (ART) has dramatically increased in recent times. This review focuses on HIV-associated heart failure in sub-Saharan Africa (SSA). In HIV infected persons, heart failure may be related to pathology of the pericardium, the myocardium, the valves, the conduction system, or the coronary and pulmonary vasculature.

View Full Text PDF Listings View primary source full text article PDFs.

Nov
2017

HIV and myocarditis.

Curr Opin HIV AIDS 2017 Nov;12(6):561-565
Ntobeko A B Ntusi
The purpose of this article is to review the literature on HIV and myocarditis and HIV-associated heart failure.
Currently, 17 million people are receiving antiretroviral therapy (ART) globally. There is a decrease in mortality from HIV in the last decade with increased survival in those receiving ART.

View Full Text PDF Listings View primary source full text article PDFs.


View Full Text PDF Listings View primary source full text article PDFs.

View Full Text PDF Listings View primary source full text article PDFs.

May
2016

Pheochromocytoma is associated with catecholamine-induced cardiac toxicity, but the extent and nature of cardiac involvement in clinical cohorts is not well-characterized.
This study characterized the cardiac phenotype in patients with pheochromocytoma using cardiac magnetic resonance (CMR).
A total of 125 subjects were studied, including patients with newly diagnosed pheochromocytoma (n = 29), patients with previously surgically cured pheochromocytoma (n = 31), healthy control subjects (n = 51), and hypertensive control subjects (HTN) (n = 14), using CMR (1.

View Full Text PDF Listings View primary source full text article PDFs.

View Full Text PDF Listings View primary source full text article PDFs.

Aug
2015

Fits, faints and funny turns.

S Afr Med J 2015 Aug;105(8):689
Ntobeko A B Ntusi

View Full Text PDF Listings View primary source full text article PDFs.

May
2015

The goal of this study was to assess the diffuse myocardial fibrosis and edema in rheumatoid arthritis (RA) using multiparametric cardiac magnetic resonance (CMR) and the association of myocardial T1 and extracellular volume (ECV) with disease activity, duration, and cardiac function.
RA is a connective tissue disorder, with frequent cardiovascular disease. Myocardial inflammation and diffuse fibrosis can be detected noninvasively by using native T1 mapping and ECV quantification on CMR.

View Full Text PDF Listings View primary source full text article PDFs.

May
2015

To investigate for the first time the feasibility of aortic four-dimensional (4D) flow at 7T, both contrast enhanced (CE) and non-CE. To quantify the signal-to-noise ratio (SNR) in aortic 4D flow as a function of field strength and CE with gadobenate dimeglumine (MultiHance).
Six healthy male volunteers were scanned at 1.

View Full Text PDF Listings View primary source full text article PDFs.

Mar
2014

Systemic sclerosis (SSc) is characterised by multi-organ tissue fibrosis including the myocardium. Diffuse myocardial fibrosis can be detected non-invasively by T1 and extracellular volume (ECV) quantification, while focal myocardial inflammation and fibrosis may be detected by T2-weighted and late gadolinium enhancement (LGE), respectively, using cardiovascular magnetic resonance (CMR). We hypothesised that multiparametric CMR can detect subclinical myocardial involvement in patients with SSc.

View Full Text PDF Listings View primary source full text article PDFs.

Jan
2014

Cardiovascular magnetic resonance (CMR) is regarded as the gold standard for clinical assessment of the aorta, but normal dimensions are usually referenced to echocardiographic and computed tomography data and no large CMR normal reference range exists. As a result we aimed to 1) produce a normal CMR reference range of aortic diameters and 2) investigate the relationship between regional aortic size and body surface area (BSA) in a large group of healthy subjects with no vascular risk factors.
447 subjects (208 male, aged 19-70 years) without identifiable cardiac risk factors (BMI range 15.

View Full Text PDF Listings View primary source full text article PDFs.

Jan
2013

Quantitative T1-mapping is rapidly becoming a clinical tool in cardiovascular magnetic resonance (CMR) to objectively distinguish normal from diseased myocardium. The usefulness of any quantitative technique to identify disease lies in its ability to detect significant differences from an established range of normal values. We aimed to assess the variability of myocardial T1 relaxation times in the normal human population estimated with recently proposed Shortened Modified Look-Locker Inversion recovery (ShMOLLI) T1 mapping technique.

View Full Text PDF Listings View primary source full text article PDFs.

Nov
2010

Adenosine is the most widely used vasodilator stress agent for cardiovascular magnetic resonance (CMR) perfusion studies. With the standard dose of 140 mcg/kg/min some patients fail to demonstrate characteristic haemodynamic changes: a significant increase in heart rate (HR) and mild decrease in systolic blood pressure (SBP). Whether an increase in the rate of adenosine infusion would improve peripheral and, likely, coronary vasodilatation in those patients is unknown.

View Full Text PDF Listings View primary source full text article PDFs.

Back to top