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Author: Sarah Ford (20)


Jun
2017

We present here the draft genome sequence ofstrain M3KCL. The assembly contains 1,864,059 bp in 60 contigs. This strain is an M3 strain close to MGAS315 but produces SpeB.

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Jun
2017

During withdrawal, nicotine users experience aversive withdrawal symptoms, such as increased nociceptive processing, which may be responsible for subsequent use. Smokers often consume more caffeine than non-smokers and the combined effects of these two psychoactive drugs result in an enhanced analgesic effect of nicotine. We examined the effects of caffeine (via coffee consumption) and nicotine withdrawal on pain perception in minimally deprived smokers and non-smokers.

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Sep
2015

We investigated rates of psychosis-related and hospital-related post-traumatic stress disorder (PTSD) in people with psychosis in secure settings. We also investigated relationships between PTSD symptoms and previous experiences of trauma and adult attachment.
Using a cross-sectional design, 50 participants from medium-secure and low-secure settings were interviewed to identify distressing experiences related to psychosis and hospitalization.

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Oct
2013

This study describes the mental illness and psychosocial outcomes of adolescents who experienced a depressive disorder and identifies predictors of full remission and recurrence.
140 adolescents with major depressive disorder, dysthymic disorder, or depressive disorder NOS were offered psychosocial and/or antidepressant treatment across two clinical trials. Three to nine years later (mean 5.

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Jun
2013

There is evidence of high rates of PTSD in people with psychosis, but the influence that symptoms or hospitalisation have on PTSD in individuals with psychosis is less clear. This paper reviewed studies investigating the prevalence of PTSD induced as a result of the experience of psychosis and hospitalisation and factors that might influence its development. The review included 24 studies, published between 1980 and 2011.

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Nov
2012

Coeliac disease (CD) is an autoimmune condition managed by a lifelong therapeutic gluten-free diet. Previous research suggests that the chronicity of CD, the limitations imposed by the gluten-free diet, and the risk of other associated diseases can have a negative impact on health-related quality of life (HRQoL) and psychological well-being. The aim of this study was to explore the illness perceptions and self-efficacy beliefs of adults with CD in the United Kingdom and to report their subjective levels of HRQoL and psychological well-being.

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Feb
2012

There is little data available on the prevalence of violence risk factors in people at ultra-high risk of developing psychosis.
The aim of this study was to provide an estimate of the cross-sectional prevalence of violence risk factors in those attending a routine clinical service for people at ultra-high risk of developing psychosis.
The case notes of all 34 clients receiving treatment over a 4-week period were reviewed and all clinicians were interviewed.

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Nov
2011

Eighty girls and 64 boys (M= 6 years; 8 months, SD= .65) narrated a wordless picture book in mixed- or same-gender dyads. In mixed-gender as well as same-gender dyads, girls used more emotion explanations than did boys.

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Sep
2008

Many patients treated with vitamin K antagonists have unstable International Normalized Ratios (INRs), increasing the risk of thrombosis and bleeding events. Changes in dietary vitamin K intake are known to lead to INR variability. Therefore, it has been hypothesized that providing stable intake of vitamin K through daily supplementation may lead to decreased INR variability.

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Oct
2008

Cachexia is common in chronic heart failure (CHF) and may be due to a combination of reduced appetite, and increased metabolic rate due to immune activation. This hypermetabolism, with an increase in acute phase protein turnover, also seen in cancer cachexia, might contribute to weight loss seen in severe CHF. We investigated the rate of hepatic fibrinogen synthesis by measuring the rate of incorporation of deuterated phenylalanine into circulating plasma fibrinogen.

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Oct
2008

Patients with atrial fibrillation (AF) who also have heart failure have a worse outcome but the diagnosis of heart failure is often missed.
To compare the effects of warfarin and ximelagatran on morbidity and mortality in patients with AF with and without markers of heart failure.
Data for 7329 patients from two randomised controlled trials were merged.

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Aug
2007

It is not known whether patients on oral vitamin K antagonists who have unstable INRs achieve more stable INRs with daily vitamin K supplementation. We sought to determine whether vitamin K supplementation may decrease INR variability in patients with a history of unstable INRs, how soon the INR decreases after vitamin K therapy is initiated, the time to reach a therapeutic INR after vitamin K initiation, and how much of an increase in oral anticoagulant dose is needed to maintain the INR in the desired range.
This is a prospective open label crossover study of patients on warfarin with a history of fluctuating INRs.

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Jun
2006

To investigate opportunities for, and types of decision making in the general practice (primary care) consultation, and examine differences in skills of those doctors who are successful at meeting their patients' preferences and those who are less successful.
Observation study of doctor-patient consultations in general practice.
Patients attending for routine appointments in 12 general practice surgeries across Oxfordshire.

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Sep
2004

The Medical Interaction Process System (MIPS) was originally developed in order to create a reliable observation tool for analysing doctor-patient encounters in the oncology setting. This paper reports a series of analyses carried out to establish whether the behaviour categories of the MIPS can discriminate between skilled and less skilled communicators. This involved the use of MIPS coded cancer consultations to compare the MIPS indices of 10 clinicians evaluated by an independent professional as skilled communicators with 10 who were considered less skilled.

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Mar
2003

To investigate the information and decision-making expectations of general practice patients during real life consultations.
Post-consultation, quantitative patient preference and enablement questionnaire.
Patients attending for routine appointments in general practice surgeries in Oxfordshire, UK.

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Feb
2003

The evidence-based patient choice (EBPC) approach is one of a number of newly emerging templates for medical encounters that advocate evidence-informed choice and shared decision-making. These models emphasise respect for patient preferences for involvement in health care decisions and advocate the sharing of good quality evidence-based information. In the medical consultation EBPC involves providing patients with evidence-based information in a way that facilitates their ability to make choices or decisions about their health care.

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Jun
2002

This study was conducted to explore barriers to the implementation of the 'evidence-based patient choice' (EBPC) consultation in medical practice. The theory behind EBPC encompasses the idea that patients should be provided with evidence-based information in a way that facilitates their ability to make choices or decisions about their health care. Semi-structured interviews were conducted with purposively selected general practitioners (GPs) (n=11), hospital doctors (n=10), practice nurses (n=5), academics (n=11) and lay people (n=8).

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