Author: Sinem Balta Beylergil (1)
Dorsolateral prefrontal cortex contributes to the impaired behavioral adaptation in alcohol dependence.Neuroimage Clin 2017 17;15:80-94. Epub 2017 Apr 17.Sinem Balta Beylergil, Anne Beck, Lorenz Deserno, Robert C Lorenz, Michael A Rapp, Florian Schlagenhauf, Andreas Heinz, Klaus Obermayer
Substance-dependent individuals often lack the ability to adjust decisions flexibly in response to the changes in reward contingencies. Prediction errors (PEs) are thought to mediate flexible decision-making by updating the reward values associated with available actions. In this study, we explored whether the neurobiological correlates of PEs are altered in alcohol dependence.
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